Endodontic biofilms: contemporary and future treatment options
유연지, Perinpanayagam Hiran, 오소람, 김아름, 한승현, 금기연,
소속 상세정보
유연지 ( Yoo Yeon-Jee ) - Seoul National University School of Dentistry Department of Conservative Dentistry
( Perinpanayagam Hiran ) - University of Western Ontario Schulich School of Medicine and Dentistry
오소람 ( Oh So-Ram ) - Kyung hee University School of Dentistry Department of Conservative Dentistry
김아름 ( Kim A-Reum ) - Seoul National University School of Dentistry Department of Oral Microbiology and Immunology
한승현 ( Han Seung-Hyun ) - Seoul National University School of Dentistry Department of Oral Microbiology and Immunology
금기연 ( Kum Kee-Yeon ) - Seoul National University School of Dentistry Department of Conservative Dentistry
Abstract
Apical periodontitis is a biofilm-mediated infection. The biofilm protects bacteria from host defenses and increase their resistance to intracanal disinfecting protocols. Understanding the virulence of these endodontic microbiota within biofilm is essential for the development of novel therapeutic procedures for intracanal disinfection. Both the disruption of biofilms and the killing of their bacteria are necessary to effectively treat apical periodontitis. Accordingly, a review of endodontic biofilm types, antimicrobial resistance mechanisms, and current and future therapeutic procedures for endodontic biofilm is provided.
키워드
Antimicrobial resistance; Endodontic biofilm; Intracanal disinfection; Lactobacillus; Lipoteichoic acid
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